HitPredict

Interactor 1: CIA2A (Q9H5X1)
Cytosolic iron-sulfur assembly component 2A (MIP18 family protein FAM96A)
Gene: CIAO2A

Interactor 2: AAAS (Q9NRG9)
Aladin (Adracalin)
Gene: AAAS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FeS_assembly_P~WD40
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 546
+	Hs
		793031 CIA2A_HUMAN (1-160): 3.04e-89: 258: 100.00		LIS1_HUMAN (314-532): 8.43e-23: 102: 10.13
+	Sc
		630861 YHS2_YEAST (25-157): 5.05e-53: 169: 43.70		NLE1_YEAST (242-538): 7.26e-41: 156: 13.03
+	Hs
		283023 CIA2A_HUMAN (1-160): 3.04e-89: 258: 100.00		CIAO1_HUMAN (197-315): 1.69e-10: 64.4: 27.27
+	Hs
		793045 CIA2B_HUMAN (37-156): 1.67e-57: 178: 55.00		LIS1_HUMAN (314-532): 8.43e-23: 102: 10.13
+	Dm
		1179144 GALL1_DROME (21-160): 1.27e-65: 200: 57.45		CIAO1_DROME (72-315): 3.97e-11: 66.4: 15.75
+	Dm
		1179145 GALL2_DROME (38-156): 5.17e-58: 179: 55.46		CIAO1_DROME (72-315): 3.97e-11: 66.4: 15.75
+	Sc
		755929 YHS2_YEAST (25-157): 5.05e-53: 169: 43.70		CIAO1_YEAST (166-353): 2.01e-14: 76.4: 18.72
+	Hs
		283065 CIA2B_HUMAN (37-156): 1.67e-57: 178: 55.00		CIAO1_HUMAN (197-315): 1.69e-10: 64.4: 27.27