HitPredict

Interactor 1: YTDC2 (Q9H6S0)
3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2) (hYTHDC2)
Gene: YTHDC2

Interactor 2: LN28A (Q9H9Z2)
Protein lin-28 homolog A (Lin-28A) (Zinc finger CCHC domain-containing protein 1)
Gene: LIN28A

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 34816099
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1430 Hs			1 209
+	Hs
		1332463 YTDC2_HUMAN (1-1430): 0: 1502: 100.00		YBOX2_HUMAN (16-199): 1.7e-44: 153: 23.86
+	Hs
		1055482 DHX8_HUMAN (25-482): 1.24e-127: 428: 22.61		LN28A_HUMAN (1-209): 2.97e-84: 250: 100.00
+	Hs
		195553 DHX15_HUMAN (164-482): 6.33e-112: 374: 26.65		LN28A_HUMAN (1-209): 2.97e-84: 250: 100.00
+	Mm
		1225249 DHX36_MOUSE (71-521): 8.25e-99: 342: 27.93		LN28A_MOUSE (1-209): 1.96e-86: 255: 96.65
+	Hs
		1329666 DHX36_HUMAN (71-521): 4.15e-100: 346: 27.63		LN28A_HUMAN (1-209): 2.97e-84: 250: 100.00
+	Hs
		994342 DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77		LN28A_HUMAN (1-209): 2.97e-84: 250: 100.00
+	Hs
		1168949 DHX36_HUMAN (71-521): 4.15e-100: 346: 27.63		LN28B_HUMAN (11-205): 3.72e-64: 200: 66.67
+	Hs
		1329690 DHX36_HUMAN (71-521): 4.15e-100: 346: 27.63		YBOX2_HUMAN (16-199): 1.7e-44: 153: 23.86
+	Hs
		1158125 DHX57_HUMAN (155-408): 6.08e-60: 229: 49.23		LN28A_HUMAN (1-209): 2.97e-84: 250: 100.00
+	Hs
		931112 DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77		YBOX1_HUMAN (26-201): 4.67e-34: 125: 21.16
+	Hs
		1158067 DHX57_HUMAN (155-408): 6.08e-60: 229: 49.23		LN28B_HUMAN (11-205): 3.72e-64: 200: 66.67
+	Hs
		1184042 DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39		LN28A_HUMAN (1-209): 2.97e-84: 250: 100.00
+	Hs
		914739 DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77		CNBP_HUMAN (123-200): 4.23e-16: 74.6: 23.75
+	Hs
		1158154 DHX57_HUMAN (155-408): 6.08e-60: 229: 49.23		YBOX2_HUMAN (16-199): 1.7e-44: 153: 23.86
+	Hs
		1184102 DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39		YBOX2_HUMAN (16-199): 1.7e-44: 153: 23.86
+	Hs
		931237 DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39		YBOX1_HUMAN (26-201): 4.67e-34: 125: 21.16
+	Hs
		914773 DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39		CNBP_HUMAN (123-200): 4.23e-16: 74.6: 23.75