HitPredict

Interactor 1: YTDC2 (Q9H6S0)
3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2) (hYTHDC2)
Gene: YTHDC2

Interactor 2: BRD7 (Q9NPI1)
Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1)
Gene: BRD7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	30940648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1430 Hs			1 651
+	Hs
		224848 DHX16_HUMAN (27-482): 4.31e-119: 401: 23.05		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		195555 DHX15_HUMAN (164-482): 6.33e-112: 374: 26.65		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		1329671 DHX36_HUMAN (71-521): 4.15e-100: 346: 27.63		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		1220290 DHX40_HUMAN (191-481): 5.27e-100: 340: 25.40		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		1332390 DHX33_HUMAN (140-476): 6.02e-99: 335: 25.57		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		994351 DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		1158128 DHX57_HUMAN (155-408): 6.08e-60: 229: 49.23		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		998933 PRP16_HUMAN (25-482): 4.04e-118: 402: 22.57		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		224782 DHX16_HUMAN (27-482): 4.31e-119: 401: 23.05		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		631533 PRP16_HUMAN (25-482): 4.04e-118: 402: 22.57		BRD2_HUMAN (115-424): 3.01e-33: 138: 15.39
+	Hs
		195410 DHX15_HUMAN (164-482): 6.33e-112: 374: 26.65		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	At
		1105309 DEAH5_ARATH (23-482): 3.84e-128: 429: 21.37		GCN5_ARATH (133-224): 9.79e-21: 98.4: 29.03
+	Sc
		859417 PRP43_YEAST (103-482): 1.24e-115: 383: 26.08		GCN5_YEAST (119-235): 2.37e-36: 143: 29.92
+	Hs
		999085 DHX36_HUMAN (71-521): 4.15e-100: 346: 27.63		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		994129 DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		600181 DHX40_HUMAN (191-481): 5.27e-100: 340: 25.40		TAF1_HUMAN (58-534): 1.25e-34: 143: 13.99
+	Hs
		631494 DHX40_HUMAN (191-481): 5.27e-100: 340: 25.40		BRD2_HUMAN (115-424): 3.01e-33: 138: 15.39
+	Hs
		1220277 DHX40_HUMAN (191-481): 5.27e-100: 340: 25.40		BRD8_HUMAN (2-261): 5.61e-27: 119: 16.23
+	Hs
		998816 DHX57_HUMAN (155-408): 6.08e-60: 229: 49.23		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		998837 DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02