HitPredict

Interactor 1: YTDC2 (Q9H6S0)
3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2) (hYTHDC2)
Gene: YTHDC2

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35915203
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~DEAD
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1430 Hs			1 2610
+	Hs
		1055512 DHX8_HUMAN (25-482): 1.24e-127: 428: 22.61		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1329686 DHX36_HUMAN (71-521): 4.15e-100: 346: 27.63		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1332393 DHX33_HUMAN (140-476): 6.02e-99: 335: 25.57		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1190226 DHX29_HUMAN (139-425): 6.43e-94: 334: 39.32		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		994392 DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1158143 DHX57_HUMAN (155-408): 6.08e-60: 229: 49.23		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1184088 DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		125714 YTDC2_HUMAN (1-1430): 0: 1502: 100.00		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		195293 DHX15_HUMAN (164-482): 6.33e-112: 374: 26.65		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		1329678 DHX36_HUMAN (71-521): 4.15e-100: 346: 27.63		HECW2_HUMAN (1360-2609): 2.26e-127: 444: 14.40
+	Hs
		304237 DHX40_HUMAN (191-481): 5.27e-100: 340: 25.40		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		125014 DHX15_HUMAN (164-482): 6.33e-112: 374: 26.65		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		994346 DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77		SMUF1_HUMAN (2220-2607): 1.5e-116: 391: 19.70
+	Hs
		125550 DHX29_HUMAN (139-425): 6.43e-94: 334: 39.32		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125408 DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125522 DHX57_HUMAN (155-408): 6.08e-60: 229: 49.23		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125542 DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Sc
		589429 PRP2_YEAST (623-1009): 8.16e-32: 137: 27.92		RSP5_YEAST (2265-2608): 2.06e-105: 360: 20.86