Interactor 1: AZI2 (Q9H6S1)
5-azacytidine-induced protein 2 (NF-kappa-B-activating kinase-associated protein 1) (Nak-associated protein 1) (Nap1) (TILP)
Gene: AZI2

Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.762

The method score is based on:

Property Details
Experiments 27620379, 21903422, 14560022, 17568778, 30420664, 29395067, 32707033, 36736316, 23286385, 14743216, 19820708, 29251827, 21931555
Identification Methods x-ray crystallography, pull down, affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation, two hybrid, in-gel kinase assay, anti bait coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type association, direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0007249 - canonical NF-kappaB signal transduction
GO:0044565 - dendritic cell proliferation
GO:0051607 - defense response to virus
GO:0060337 - type I interferon-mediated signaling pathway
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 392
Hs

1 729
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024