Interactor 1: RPAP3 (Q9H6T3)
RNA polymerase II-associated protein 3
Gene: RPAP3

Interactor 2: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 28561026, 33961781, 35271311, 17643375, 19180575, 29662061, 31738558, 19450687, 25036637
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RPAP3_C~TIP49_C
Common GO terms GO:0005829 - cytosol
GO:0050821 - protein stabilization
GO:0097255 - R2TP complex
GO:0101031 - protein folding chaperone complex
GO:1990062 - RPAP3/R2TP/prefoldin-like complex
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 665
Hs

1 463
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Last updated: 15 Jul 2024