Interactor 1: RPAP3 (Q9H6T3)
RNA polymerase II-associated protein 3
Gene: RPAP3

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 28514442, 28561026, 33961781, 35271311, 20371770, 29662061, 31738558, 19450687, 25036637
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RPAP3_C~TIP49_C
Common GO terms GO:0005829 - cytosol
GO:0050821 - protein stabilization
GO:0097255 - R2TP complex
GO:0101031 - protein folding chaperone complex
GO:1990062 - RPAP3/R2TP/prefoldin-like complex
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 665
Hs

1 456
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm
+ Hs
+ Mm
+ Dm
+ Hs
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024