HitPredict

Interactor 1: MAGIX (Q9H6Y5)
PDZ domain-containing protein MAGIX
Gene: MAGIX

Interactor 2: ZO2 (Q9UDY2)
Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2)
Gene: TJP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Guanylate_kin~PDZ, PDZ~PDZ, PDZ~SH3_2
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 1190
+	Hs
		1293407 PDLI5_HUMAN (124-333): 6.16e-34: 133: 25.55		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Hs
		990934 MAGIX_HUMAN (1-334): 1.83e-54: 182: 100.00		ZO1_HUMAN (19-1187): 5.94e-133: 447: 36.80
+	Rn
		1144009 DLG1_RAT (3-210): 1.51e-26: 112: 17.21		CSKP_RAT (229-890): 1.15e-93: 323: 15.72
+	Mm
		251104 DLG1_MOUSE (3-217): 1.66e-26: 112: 16.22		CSKP_MOUSE (229-890): 6.48e-93: 321: 15.09
+	Hs
		159190 DLG4_HUMAN (79-217): 1.08e-25: 109: 21.13		CSKP_HUMAN (229-890): 6.3e-93: 321: 15.09
+	Rn
		677787 DLG1_RAT (3-210): 1.51e-26: 112: 17.21		DLG4_RAT (3-423): 1.74e-52: 199: 18.89
+	Hs
		942349 DLG2_HUMAN (57-210): 1.6e-26: 112: 18.87		DLG4_HUMAN (3-423): 2.31e-52: 199: 18.89
+	Mm
		1143387 DLG1_MOUSE (3-217): 1.66e-26: 112: 16.22		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		1143467 DLG2_MOUSE (57-210): 2.14e-26: 112: 18.87		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Hs
		942321 DLG4_HUMAN (79-217): 1.08e-25: 109: 21.13		DLG4_HUMAN (3-423): 2.31e-52: 199: 18.89
+	Hs
		1021501 DLG2_HUMAN (57-210): 1.6e-26: 112: 18.87		DLG1_HUMAN (1-515): 2.7e-47: 185: 16.38
+	Rn
		1144014 DLG1_RAT (3-210): 1.51e-26: 112: 17.21		DLG2_RAT (8-534): 1.37e-45: 179: 15.41
+	Hs
		303748 MAGIX_HUMAN (1-334): 1.83e-54: 182: 100.00		ZO3_HUMAN (3-520): 5.13e-13: 75.9: 13.38
+	Hs
		1077285 DLG2_HUMAN (57-210): 1.6e-26: 112: 18.87		DLG3_HUMAN (2-318): 5.99e-23: 107: 16.61
+	Hs
		942364 DLG4_HUMAN (79-217): 1.08e-25: 109: 21.13		DLG3_HUMAN (2-318): 5.99e-23: 107: 16.61
+	Rn
		1144010 DLG1_RAT (3-210): 1.51e-26: 112: 17.21		DLG3_RAT (372-595): 5.53e-13: 75.5: 18.10
+	Mm
		936188 DLG2_MOUSE (57-210): 2.14e-26: 112: 18.87		DLG3_MOUSE (372-595): 5.97e-13: 75.5: 18.10