HitPredict

Interactor 1: SH24A (Q9H788)
SH2 domain-containing protein 4A (Protein SH(2)A) (Protein phosphatase 1 regulatory subunit 38)
Gene: SH2D4A

Interactor 2: TRIM1 (Q9UJV3)
Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1)
Gene: MID2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	unassigned1654
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 735
+	Hs
		50976 SH24A_HUMAN (1-454): 1.2e-138: 407: 100.00		FSD2_HUMAN (206-712): 2.04e-81: 276: 22.86
+	Hs
		1317445 SH24A_HUMAN (1-454): 1.2e-138: 407: 100.00		TRI54_HUMAN (184-400): 2.63e-53: 190: 23.96
+	Hs
		537069 SH24A_HUMAN (1-454): 1.2e-138: 407: 100.00		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		734772 SH24A_HUMAN (1-454): 1.2e-138: 407: 100.00		TRI23_HUMAN (28-272): 6.41e-17: 86.7: 24.71
+	Hs
		522983 SRC_HUMAN (238-454): 4.15e-42: 158: 14.56		TRI25_HUMAN (24-706): 9.41e-99: 319: 20.96
+	Hs
		1172216 VAV3_HUMAN (161-444): 7.84e-42: 160: 15.46		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		561394 FER_HUMAN (147-445): 1.31e-41: 159: 16.99		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		433394 YES_HUMAN (201-454): 1.68e-41: 156: 15.44		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		924655 GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		523126 SRC_HUMAN (238-454): 4.15e-42: 158: 14.56		FSD1_HUMAN (236-728): 1.79e-87: 285: 26.18
+	Hs
		581017 PLCG1_HUMAN (90-454): 1.69e-25: 112: 14.47		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		655365 P85A_HUMAN (341-451): 2.42e-18: 90: 24.14		TRI25_HUMAN (24-706): 9.41e-99: 319: 20.96
+	Hs
		129310 P85B_HUMAN (134-447): 1.04e-20: 97.3: 16.97		TRI67_HUMAN (74-718): 5.93e-89: 297: 22.96
+	Hs
		50942 Q8N381_HUMAN (341-451): 1.34e-18: 90: 21.55		FSD2_HUMAN (206-712): 2.04e-81: 276: 22.86
+	Hs
		924879 GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83		TRI39_HUMAN (21-389): 6.9e-27: 117: 12.81
+	Hs
		536781 GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		924728 GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83		SPRY4_HUMAN (536-708): 2.31e-16: 80.1: 28.98
+	Mm
		1143604 PLCG2_MOUSE (98-454): 9.41e-29: 121: 15.03		TRI27_MOUSE (16-340): 3.65e-24: 109: 14.15
+	Hs
		129226 P85B_HUMAN (134-447): 1.04e-20: 97.3: 16.97		TRI23_HUMAN (28-272): 6.41e-17: 86.7: 24.71
+	Hs
		581005 PLCG1_HUMAN (90-454): 1.69e-25: 112: 14.47		TRI14_HUMAN (192-413): 5.06e-11: 67.6: 19.30