Interactor 1: MLKL (Q8NB16)
Mixed lineage kinase domain-like protein (hMLKL)
Gene: MLKL
Interactor 2: LRCH3 (Q96II8)
DISP complex protein LRCH3 (Leucine-rich repeat and calponin homology domain-containing protein 3)
Gene: LRCH3
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26496610 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CH~PK_Tyr_Ser-Thr, LRR_8~PK_Tyr_Ser-Thr |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
