HitPredict

Interactor 1: SDS3 (Q9H7L9)
Sin3 histone deacetylase corepressor complex component SDS3 (45 kDa Sin3-associated polypeptide) (Suppressor of defective silencing 3 protein homolog)
Gene: SUDS3

Interactor 2: BRMS1 (Q9HCU9)
Breast cancer metastasis-suppressor 1
Gene: BRMS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

The method score is based on:

Property	Details
Experiments	14581478, 16919237
Identification Methods	two hybrid, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006915 - apoptotic process GO:0030336 - negative regulation of cell migration and 6 others more... GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway GO:0042826 - histone deacetylase binding GO:0045892 - negative regulation of DNA-templated transcription GO:0070822 - Sin3-type complex GO:1902455 - negative regulation of stem cell population maintenance GO:1902459 - positive regulation of stem cell population maintenance
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	328
Hs

1	246

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024