HitPredict

Interactor 1: KAT8 (Q9H7Z6)
Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (Males-absent on the first protein homolog) (hMOF) (Protein acetyltransferase KAT8) (EC 2.3.1.-) (Protein propionyltransferase KAT8) (EC 2.3.1.-)
Gene: KAT8

Interactor 2: KAT8 (Q9H7Z6)
Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (Males-absent on the first protein homolog) (hMOF) (Protein acetyltransferase KAT8) (EC 2.3.1.-) (Protein propionyltransferase KAT8) (EC 2.3.1.-)
Gene: KAT8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 15960975, 21502975
Identification Methods affinity chromatography technology, enzymatic study, pull down
Interaction Type physical association, direct interaction, acetylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains MOZ_SAS~MOZ_SAS, MOZ_SAS~zf-MYST, Tudor-knot~Tudor-knot
Common GO terms GO:0000123 - histone acetyltransferase complex
GO:0000776 - kinetochore
GO:0003682 - chromatin binding
GO:0003712 - transcription coregulator activity
GO:0003713 - transcription coactivator activity
and 32 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 458
Hs

1 458
+ Dm
+ Sc
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024