Interactor 1: RMD5A (Q9H871)
E3 ubiquitin-protein transferase RMND5A (EC 2.3.2.27) (P44CTLH) (Protein RMD5 homolog A)
Gene: RMND5A

Interactor 2: GID8 (Q9NWU2)
Glucose-induced degradation protein 8 homolog (Two hybrid-associated protein 1 with RanBPM) (Twa1)
Gene: GID8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 26186194, 28514442, 29911972, 33961781, 27173435, 32296183, 17467196, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, pull down, tandem affinity purification, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CTLH~CTLH, CTLH~LisH
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 391
Hs

1 228
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024