HitPredict

Interactor 1: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Interactor 2: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31353912
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 626 Hs			1 2581
+	Hs
		903535 WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23		CHD8_HUMAN (1-2581): 0: 2318: 100.00
+	Hs
		1059879 WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		229498 WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00		SMCA5_HUMAN (687-1722): 0: 886: 26.82
+	Hs
		1018714 NLE1_HUMAN (181-575): 1.3e-63: 219: 12.70		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1059779 FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		197011 PRP4_HUMAN (401-624): 5.45e-40: 155: 15.09		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1018633 SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		903234 WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		197020 PRP4_HUMAN (401-624): 5.45e-40: 155: 15.09		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		658714 FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79		SMCA1_HUMAN (654-1705): 0: 875: 26.13
+	Sc
		697460 CMR1_YEAST (159-623): 1.38e-74: 249: 23.50		CHD1_YEAST (589-1846): 0: 853: 26.22
+	Hs
		151440 FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79		CHD1_HUMAN (530-1808): 0: 828: 27.06
+	Hs
		847050 FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79		SMCA4_HUMAN (69-1478): 0: 806: 23.14
+	Hs
		658715 SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83		SMCA1_HUMAN (654-1705): 0: 875: 26.13
+	Hs
		151443 SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83		CHD1_HUMAN (530-1808): 0: 828: 27.06
+	Hs
		847053 SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83		SMCA4_HUMAN (69-1478): 0: 806: 23.14
+	Hs
		1254435 FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79		CHD6_HUMAN (1354-2489): 1.68e-106: 385: 14.08
+	Hs
		1334036 WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00		CHD7_HUMAN (7-828): 2.19e-22: 108: 8.97
+	Ce
		954000 LIN53_CAEEL (251-477): 2.75e-20: 95.7: 15.73		CHD3_CAEEL (1744-2065): 7.9e-56: 218: 12.68
+	Ce
		104626 LIN53_CAEEL (251-477): 2.75e-20: 95.7: 15.73		LE418_CAEEL (1876-2045): 1.12e-20: 102: 17.05