HitPredict

Interactor 1: ARP8 (Q9H981)
Actin-related protein 8 (hArp8) (INO80 complex subunit N)
Gene: ACTR8

Interactor 2: ARP5 (Q9H9F9)
Actin-related protein 5 (hARP5) (Sarcoma antigen NY-SAR-16)
Gene: ACTR5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.887

The method score is based on:

Property Details
Experiments 26496610, 17721549, 18163988, 16230350
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Actin
Common GO terms GO:0000723 - telomere maintenance
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006275 - regulation of DNA replication
GO:0006282 - regulation of DNA repair
and 12 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 624
Hs

1 607
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+ Ce
+ Ce
+ Ce
+ Dm
+ Dm
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+ Gg
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024