HitPredict

Interactor 1: ARP8 (Q9H981)
Actin-related protein 8 (hArp8) (INO80 complex subunit N)
Gene: ACTR8

Interactor 2: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.945

The method score is based on:

Property Details
Experiments 33961781, 35271311, 17643375, 17721549, 28514442, 16230350
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~TIP49
Common GO terms GO:0000723 - telomere maintenance
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005813 - centrosome
and 13 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 624
Hs

1 463
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024