HitPredict

Interactor 1: RPA2 (Q9H9Y6)
DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135)
Gene: POLR1B

Interactor 2: GPN3 (Q9UHW5)
GPN-loop GTPase 3 (ATP-binding domain 1 family member C)
Gene: GPN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1135 Hs			1 284
+	Hs
		1334509 RPA2_HUMAN (1-1135): 0: 1519: 100.00		GPN1_HUMAN (3-251): 6.08e-98: 293: 25.40
+	Hs
		677049 RPB2_HUMAN (18-1135): 0: 1296: 27.87		GPN3_HUMAN (1-284): 1.23e-155: 437: 100.00
+	Hs
		677010 RPB2_HUMAN (18-1135): 0: 1296: 27.87		GPN2_HUMAN (4-254): 1.73e-132: 379: 42.13
+	Hs
		1347027 RPC2_HUMAN (12-1134): 0: 1210: 28.58		GPN3_HUMAN (1-284): 1.23e-155: 437: 100.00
+	Hs
		677015 RPB2_HUMAN (18-1135): 0: 1296: 27.87		GPN1_HUMAN (3-251): 6.08e-98: 293: 25.40
+	Sc
		440105 RPB2_YEAST (18-1132): 0: 1227: 26.50		GPN3_YEAST (1-268): 5.79e-122: 351: 43.17
+	Sc
		606767 RPC2_YEAST (21-1134): 0: 1197: 28.27		GPN3_YEAST (1-268): 5.79e-122: 351: 43.17
+	Sc
		440113 RPB2_YEAST (18-1132): 0: 1227: 26.50		GPN2_YEAST (3-254): 8.37e-105: 310: 34.35
+	Sc
		606775 RPC2_YEAST (21-1134): 0: 1197: 28.27		GPN2_YEAST (3-254): 8.37e-105: 310: 34.35
+	Hs
		1336398 RPC2_HUMAN (12-1134): 0: 1210: 28.58		GPN1_HUMAN (3-251): 6.08e-98: 293: 25.40
+	Sc
		440060 RPB2_YEAST (18-1132): 0: 1227: 26.50		GPN1_YEAST (1-284): 1.16e-86: 265: 22.34
+	Sc
		604581 RPA2_YEAST (29-1134): 0: 1219: 42.49		GPN1_YEAST (1-284): 1.16e-86: 265: 22.34
+	Sc
		606693 RPC2_YEAST (21-1134): 0: 1197: 28.27		GPN1_YEAST (1-284): 1.16e-86: 265: 22.34