HitPredict

Interactor 1: NOP56 (O00567)
Nucleolar protein 56 (Nucleolar protein 5A)
Gene: NOP56

Interactor 2: EXOS9 (Q06265)
Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75)
Gene: EXOSC9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0006364 - rRNA processing
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 594 Hs			1 439
+	Sc
		984329 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		RRP45_YEAST (2-290): 7.5e-80: 250: 33.78
+	Sc
		984330 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		RRP45_YEAST (2-290): 7.5e-80: 250: 33.78
+	Sc
		1015409 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		RRP42_YEAST (4-267): 2.09e-41: 149: 16.43
+	Sc
		809606 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		RRP41_YEAST (20-276): 9.25e-40: 144: 16.23
+	Hs
		1262974 PRP31_HUMAN (160-581): 1.53e-125: 380: 19.91		EXOS8_HUMAN (1-275): 1.68e-86: 267: 26.98
+	Sc
		1015410 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		RRP42_YEAST (4-267): 2.09e-41: 149: 16.43
+	Sc
		809607 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		RRP41_YEAST (20-276): 9.25e-40: 144: 16.23