HitPredict

Interactor 1: NOP56 (O00567)
Nucleolar protein 56 (Nucleolar protein 5A)
Gene: NOP56

Interactor 2: TBL3 (Q12788)
Transducin beta-like protein 3 (WD repeat-containing protein SAZD)
Gene: TBL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0032040 - small-subunit processome GO:0042274 - ribosomal small subunit biogenesis
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 594 Hs			1 808
+	Sc
		635672 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		PWP2_YEAST (201-754): 1.29e-77: 271: 15.11
+	Hs
		133736 NOP56_HUMAN (1-594): 0: 661: 100.00		FBW1A_HUMAN (334-642): 7.67e-24: 108: 26.17
+	Hs
		903625 NOP58_HUMAN (4-567): 0: 531: 35.39		WDR5_HUMAN (458-757): 3.76e-66: 225: 20.93
+	Hs
		133730 NOP56_HUMAN (1-594): 0: 661: 100.00		WDR3_HUMAN (2-94): 8.52e-16: 84.1: 10.64
+	Sc
		635674 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		PWP2_YEAST (201-754): 1.29e-77: 271: 15.11
+	Sc
		1015332 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		UTP12_YEAST (25-369): 4.01e-54: 204: 13.56
+	Sc
		1015334 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		UTP12_YEAST (25-369): 4.01e-54: 204: 13.56
+	Hs
		1357605 NOP58_HUMAN (4-567): 0: 531: 35.39		WDR3_HUMAN (2-94): 8.52e-16: 84.1: 10.64
+	Hs
		903389 PRP31_HUMAN (160-581): 1.53e-125: 380: 19.91		WDR5_HUMAN (458-757): 3.76e-66: 225: 20.93
+	Sc
		985444 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		UTP13_YEAST (2-93): 4.79e-15: 81.4: 12.90
+	Sc
		985446 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		UTP13_YEAST (2-93): 4.79e-15: 81.4: 12.90