HitPredict

Interactor 1: NOP56 (O00567)
Nucleolar protein 56 (Nucleolar protein 5A)
Gene: NOP56

Interactor 2: DDX10 (Q13206)
Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10)
Gene: DDX10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0006364 - rRNA processing
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 594 Hs			1 875
+	Hs
		133700 NOP56_HUMAN (1-594): 0: 661: 100.00		DDX18_HUMAN (15-556): 5.31e-149: 456: 38.57
+	Hs
		133576 NOP56_HUMAN (1-594): 0: 661: 100.00		DDX55_HUMAN (70-627): 7.77e-150: 455: 33.89
+	Dm
		1280026 Q95WY3_DROME (1-471): 0: 581: 61.67		DDX18_DROME (36-565): 8.57e-171: 513: 36.64
+	Dm
		1363481 Q9VM69_DROME (4-491): 4.2e-166: 484: 36.89		DDX18_DROME (36-565): 8.57e-171: 513: 36.64
+	Sc
		593730 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		DBP4_YEAST (31-688): 1.51e-131: 413: 40.66
+	Sc
		976894 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		HAS1_YEAST (32-510): 5.86e-123: 382: 39.34
+	Dm
		1249026 Q9VM69_DROME (4-491): 4.2e-166: 484: 36.89		Q8SY39_DROME (71-847): 1.14e-130: 413: 21.25
+	Hs
		133679 NOP56_HUMAN (1-594): 0: 661: 100.00		DDX31_HUMAN (92-509): 4.25e-64: 233: 34.20
+	Sc
		593732 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		DBP4_YEAST (31-688): 1.51e-131: 413: 40.66
+	Sc
		416116 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		DED1_YEAST (18-473): 2.54e-131: 408: 26.25
+	Hs
		133756 NOP56_HUMAN (1-594): 0: 661: 100.00		DDX49_HUMAN (71-539): 4e-51: 189: 29.88
+	Sc
		976896 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		HAS1_YEAST (32-510): 5.86e-123: 382: 39.34
+	Dm
		1367913 Q9VM69_DROME (4-491): 4.2e-166: 484: 36.89		DDX47_DROME (71-430): 6.11e-59: 211: 35.64
+	Dm
		1176766 Q9VM69_DROME (4-491): 4.2e-166: 484: 36.89		Q7JQN4_DROME (57-470): 8.31e-53: 199: 35.31