HitPredict

Interactor 1: UBTD1 (Q9HAC8)
Ubiquitin domain-containing protein 1
Gene: UBTD1

Interactor 2: UB2D4 (Q9Y2X8)
Ubiquitin-conjugating enzyme E2 D4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D4) (HBUCE1) (Ubiquitin carrier protein D4) (Ubiquitin-protein ligase D4)
Gene: UBE2D4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.80	0.789

Property	Details
Experiments	32296183, 24211586, unassigned1304, 19549727
Identification Methods	two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 227 Hs			1 147
+	Hs
		1260455 UBTD2_HUMAN (1-225): 6.55e-141: 395: 64.07		UB2D4_HUMAN (1-147): 8.89e-84: 243: 100.00
+	Dm
		639404 Q9VNB2_DROME (1-220): 9.2e-132: 372: 49.79		UBCD1_DROME (1-147): 4.66e-82: 239: 92.52
+	Hs
		849450 UBTD1_HUMAN (1-227): 1.88e-123: 350: 100.00		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		919866 UBTD1_HUMAN (1-227): 1.88e-123: 350: 100.00		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	Hs
		895917 UBTD1_HUMAN (1-227): 1.88e-123: 350: 100.00		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84