HitPredict

Interactor 1: EAF6 (Q9HAF1)
Chromatin modification-related protein MEAF6 (MYST/Esa1-associated factor 6) (Esa1-associated factor 6 homolog) (Protein EAF6 homolog) (hEAF6) (Sarcoma antigen NY-SAR-91)
Gene: MEAF6

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

The method score is based on:

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006275 - regulation of DNA replication GO:0006338 - chromatin remodeling and 7 others more... GO:0006355 - regulation of DNA-templated transcription GO:0035267 - NuA4 histone acetyltransferase complex GO:0042981 - regulation of apoptotic process GO:0045893 - positive regulation of DNA-templated transcription GO:0051726 - regulation of cell cycle GO:1905168 - positive regulation of double-strand break repair via homologous recombination GO:2000779 - regulation of double-strand break repair
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	191
Hs

1	456

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024