HitPredict

Interactor 1: PKHA5 (Q9HAU0)
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Gene: PLEKHA5

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24255178
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1116 Hs			1 1088
+	Hs
		1153402 PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		325893 PKHA5_HUMAN (1-1116): 0: 609: 100.00		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		1300675 MAGI1_HUMAN (1-1111): 1.6e-43: 175: 9.66		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1335080 PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		325772 MAGI3_HUMAN (1-1116): 3.96e-94: 331: 9.76		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		568798 PKHA5_HUMAN (1-1116): 0: 609: 100.00		KAPCA_HUMAN (635-1024): 1.31e-133: 410: 31.73
+	Hs
		325859 MAGI1_HUMAN (1-1111): 1.6e-43: 175: 9.66		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325896 PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325889 PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		568704 PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32		KAPCA_HUMAN (635-1024): 1.31e-133: 410: 31.73
+	Hs
		1069668 GAB2_HUMAN (168-641): 4.97e-48: 185: 12.25		STK38_HUMAN (583-1065): 5.24e-146: 447: 40.58
+	Hs
		682077 GAB2_HUMAN (168-641): 4.97e-48: 185: 12.25		AKT1_HUMAN (532-1043): 2.2e-141: 435: 22.16
+	Hs
		1073434 MAGI3_HUMAN (1-1116): 3.96e-94: 331: 9.76		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Sc
		765850 BOI2_YEAST (74-315): 4.44e-38: 157: 19.15		CBK1_YEAST (347-1051): 3.83e-143: 450: 29.56
+	Rn
		1144020 CAPS1_RAT (70-775): 3.49e-41: 167: 11.16		AKT3_RAT (532-1043): 9.38e-140: 431: 21.82
+	Mm
		933111 CNKR2_MOUSE (120-329): 2.5e-47: 186: 26.94		KAPCB_MOUSE (638-1022): 3.87e-133: 409: 31.62
+	Hs
		568795 PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85		KAPCA_HUMAN (635-1024): 1.31e-133: 410: 31.73
+	Hs
		1073444 MAGI2_HUMAN (4-650): 6.29e-50: 195: 11.18		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		1073470 MAGI1_HUMAN (1-1111): 1.6e-43: 175: 9.66		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		254513 PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85		ROCK2_HUMAN (640-1008): 6.33e-67: 248: 36.90