HitPredict

Interactor 1: PKHA5 (Q9HAU0)
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Gene: PLEKHA5

Interactor 2: AGAP1 (Q9UPQ3)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP-1) (Centaurin-gamma-2) (Cnt-g2) (GTP-binding and GTPase-activating protein 1) (GGAP1)
Gene: AGAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ArfGap~PH, PH~Ras
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1116 Hs			1 857
+	Hs
		1153457 PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32		AGAP1_HUMAN (1-857): 0: 850: 100.00
+	Hs
		1357703 GAB2_HUMAN (168-641): 4.97e-48: 185: 12.25		AGAP1_HUMAN (1-857): 0: 850: 100.00
+	Hs
		1300695 MAGI1_HUMAN (1-1111): 1.6e-43: 175: 9.66		AGAP1_HUMAN (1-857): 0: 850: 100.00
+	Hs
		1231307 RHG24_HUMAN (171-755): 5.66e-59: 219: 13.12		AGAP3_HUMAN (4-827): 0: 768: 72.46
+	Hs
		1190998 RHG22_HUMAN (139-751): 3.05e-43: 170: 15.09		AGAP3_HUMAN (4-827): 0: 768: 72.46
+	Mm
		1112606 CNKR2_MOUSE (120-329): 2.5e-47: 186: 26.94		AGAP2_MOUSE (53-827): 0: 579: 52.95
+	Hs
		1167408 MPRIP_HUMAN (95-395): 8.25e-38: 155: 13.86		AGAP2_HUMAN (52-827): 0: 597: 52.94
+	Hs
		1199790 MAGI2_HUMAN (4-650): 6.29e-50: 195: 11.18		Q9H4D1_HUMAN (376-855): 5.28e-87: 295: 16.17
+	Hs
		1231287 RHG24_HUMAN (171-755): 5.66e-59: 219: 13.12		ARAP2_HUMAN (556-846): 2.29e-75: 271: 27.70
+	Mm
		1148423 CNKR2_MOUSE (120-329): 2.5e-47: 186: 26.94		GIT1_MOUSE (616-848): 7.53e-73: 256: 31.58
+	Hs
		1050153 PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85		GIT2_HUMAN (616-823): 7.46e-74: 258: 33.33
+	Hs
		1331684 PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85		GIT1_HUMAN (616-848): 2.84e-73: 257: 31.58
+	Sc
		533765 BOI2_YEAST (74-315): 4.44e-38: 157: 19.15		RSR1_YEAST (69-333): 7.53e-75: 247: 19.56
+	Sc
		533759 BOB1_YEAST (129-362): 2.46e-37: 154: 17.72		RSR1_YEAST (69-333): 7.53e-75: 247: 19.56
+	Hs
		918949 PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85		RAB1A_HUMAN (72-257): 3.27e-72: 237: 24.35
+	Hs
		1066128 ACAP2_HUMAN (128-692): 2.59e-47: 184: 13.38		ACAP3_HUMAN (382-738): 1.62e-50: 193: 22.35
+	Hs
		883551 MAGI2_HUMAN (4-650): 6.29e-50: 195: 11.18		RIPK4_HUMAN (566-798): 1.5e-13: 76.7: 13.81