HitPredict

Interactor 1: PKHA3 (Q9HB20)
Pleckstrin homology domain-containing family A member 3 (PH domain-containing family A member 3) (Phosphatidylinositol-four-phosphate adapter protein 1) (FAPP-1) (Phosphoinositol 4-phosphate adapter protein 1)
Gene: PLEKHA3

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 300 Hs			1 249
+	Hs
		603095 OSBP1_HUMAN (2-299): 1.06e-52: 185: 20.91		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1282120 OSBP2_HUMAN (2-231): 7.71e-45: 164: 23.74		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1302540 OSBL9_HUMAN (1-294): 4e-43: 159: 21.54		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1315187 OSB11_HUMAN (3-298): 2.3e-42: 156: 15.82		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1315823 OSBL1_HUMAN (2-299): 7.24e-42: 155: 19.06		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Rn
		1225298 OSBL1_RAT (2-299): 2.59e-41: 154: 19.06		VAPA_RAT (1-249): 3.22e-99: 291: 96.79
+	Hs
		310506 OSBP1_HUMAN (2-299): 1.06e-52: 185: 20.91		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310745 OSBP2_HUMAN (2-231): 7.71e-45: 164: 23.74		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310768 OSBL9_HUMAN (1-294): 4e-43: 159: 21.54		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310784 OSB11_HUMAN (3-298): 2.3e-42: 156: 15.82		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310786 OSBL1_HUMAN (2-299): 7.24e-42: 155: 19.06		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Dm
		1362486 Q9VC05_DROME (1-300): 4.14e-59: 203: 22.32		Q9W4N8_DROME (15-216): 1.28e-52: 173: 37.56
+	Dm
		1362484 Q9VC05_DROME (1-300): 4.14e-59: 203: 22.32		Q9VSD3_DROME (11-201): 1.14e-46: 156: 29.02
+	At
		1258327 ORP2A_ARATH (3-261): 1.95e-36: 139: 16.10		VAP11_ARATH (8-214): 4.22e-67: 210: 25.11
+	Hs
		603075 OSBP1_HUMAN (2-299): 1.06e-52: 185: 20.91		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34
+	Hs
		1245667 OSBL1_HUMAN (2-299): 7.24e-42: 155: 19.06		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34
+	Hs
		1245691 CERT_HUMAN (3-252): 4.02e-40: 149: 19.81		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34
+	Sc
		728872 OSH1_YEAST (2-221): 1.72e-41: 155: 23.48		SCS2_YEAST (16-172): 2.69e-32: 119: 26.79
+	Sc
		1015618 OSH2_YEAST (2-278): 3.54e-38: 145: 20.70		SCS22_YEAST (18-156): 3.77e-33: 120: 26.32
+	Sc
		767991 OSH2_YEAST (2-278): 3.54e-38: 145: 20.70		SCS2_YEAST (16-172): 2.69e-32: 119: 26.79