Interactor 1: TRPV4 (Q9HBA0)
Transient receptor potential cation channel subfamily V member 4 (TrpV4) (Osm-9-like TRP channel 4) (OTRPC4) (Transient receptor potential protein 12) (TRP12) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC)
Gene: TRPV4

Interactor 2: TRPV4 (Q9HBA0)
Transient receptor potential cation channel subfamily V member 4 (TrpV4) (Osm-9-like TRP channel 4) (OTRPC4) (Transient receptor potential protein 12) (TRP12) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC)
Gene: TRPV4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 26146187, 16293632
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Ank, Ion_trans~Ion_trans
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001666 - response to hypoxia
GO:0002024 - diet induced thermogenesis
GO:0003779 - actin binding
GO:0005034 - osmosensor activity
and 70 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 871
Hs

1 871
+ Mm
+ Hs
+ Rn
+ Mm
+ Mm
+ Oc
+ Rn
+ Hs
+ Hs
+ Rn
+ Hs
+ Ce
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024