HitPredict

Interactor 1: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Interactor 2: CNOT2 (Q9NZN8)
CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2)
Gene: CNOT2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29395067, 30209976, 23663784
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1191 Hs			1 540
+	Hs
		257411 RC3H2_HUMAN (1-1191): 0: 1105: 100.00		CNOT3_HUMAN (4-524): 3.46e-106: 336: 16.19
+	Hs
		1136333 RC3H1_HUMAN (1-1108): 0: 788: 49.30		CNOT2_HUMAN (1-540): 0: 528: 100.00
+	Hs
		257363 RC3H1_HUMAN (1-1108): 0: 788: 49.30		CNOT3_HUMAN (4-524): 3.46e-106: 336: 16.19
+	Dm
		1276861 Q9VV48_DROME (1-615): 0: 665: 48.76		RGA_DROME (22-534): 6.07e-96: 305: 29.50
+	Dm
		1178912 Q9VV48_DROME (1-615): 0: 665: 48.76		Q7K126_DROME (4-525): 4.7e-76: 258: 15.41
+	Hs
		257714 ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44		CNOT2_HUMAN (1-540): 0: 528: 100.00
+	Mm
		101458 F8VPR5_MOUSE (603-1040): 1.87e-10: 67.7: 8.22		CNOT3_MOUSE (4-524): 3.42e-109: 344: 17.14
+	Hs
		257299 ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44		CNOT3_HUMAN (4-524): 3.46e-106: 336: 16.19
+	Dm
		113976 M9PB30_DROME (683-1171): 5.39e-11: 69.7: 12.25		M9PB30_DROME (37-438): 2.6e-11: 69: 13.35
+	Hs
		1336185 MAGE1_HUMAN (459-823): 2.66e-11: 70.3: 14.21		MAGE1_HUMAN (30-384): 2.34e-09: 62.1: 13.13