Interactor 1: SEN2 (Q8NCE0)
tRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2) (HsSen2)
Gene: TSEN2
Interactor 2: SEN34 (Q9BSV6)
tRNA-splicing endonuclease subunit Sen34 (EC 4.6.1.16) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)
Gene: TSEN34
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.79 | 1.00 | 0.892 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15109492, 28514442, 33961781, unassigned3799 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | tRNA_int_endo~tRNA_int_endo, tRNA_int_endo~tRNA_int_endo_N |
| Common GO terms | GO:0000213 - tRNA-intron lyase activity GO:0000214 - tRNA-intron endonuclease complex GO:0000379 - tRNA-type intron splice site recognition and cleavage GO:0003676 - nucleic acid binding GO:0005654 - nucleoplasm and 3 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
