Interactor 1: NOD2 (Q9HC29)
Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) (Inflammatory bowel disease protein 1)
Gene: NOD2

Interactor 2: NOD2 (Q9HC29)
Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) (Inflammatory bowel disease protein 1)
Gene: NOD2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.821

The method score is based on:

Property Details
Experiments 23437331, 16492792, 19337385
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CARD~CARD, LRR_6~LRR_6, NACHT~NACHT, NACHT~NLRC4_HD2, NACHT~NOD2_WH, NLRC4_HD2~NOD2_WH
Common GO terms GO:0001659 - temperature homeostasis
GO:0002221 - pattern recognition receptor signaling pathway
GO:0002227 - innate immune response in mucosa
GO:0002250 - adaptive immune response
GO:0002606 - positive regulation of dendritic cell antigen processing and presentation
and 99 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024