HitPredict

Interactor 1: NOP56 (O00567)
Nucleolar protein 56 (Nucleolar protein 5A)
Gene: NOP56

Interactor 2: WDR36 (Q8NI36)
WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP)
Gene: WDR36

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0006364 - rRNA processing GO:0032040 - small-subunit processome GO:0042274 - ribosomal small subunit biogenesis
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 594 Hs			1 951
+	Hs
		1246506 NOP58_HUMAN (4-567): 0: 531: 35.39		WDR36_HUMAN (1-951): 0: 622: 100.00
+	Sc
		985837 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		UTP21_YEAST (57-949): 1.79e-127: 410: 29.48
+	Hs
		133462 NOP56_HUMAN (1-594): 0: 661: 100.00		TBL3_HUMAN (2-361): 3.23e-60: 222: 14.88
+	Sc
		985839 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		UTP21_YEAST (57-949): 1.79e-127: 410: 29.48
+	Hs
		133730 NOP56_HUMAN (1-594): 0: 661: 100.00		WDR3_HUMAN (379-700): 3.49e-29: 127: 12.06
+	Sc
		985444 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		UTP13_YEAST (144-695): 3.95e-50: 192: 17.28
+	Hs
		1357605 NOP58_HUMAN (4-567): 0: 531: 35.39		WDR3_HUMAN (379-700): 3.49e-29: 127: 12.06
+	Sc
		985446 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		UTP13_YEAST (144-695): 3.95e-50: 192: 17.28
+	Hs
		903625 NOP58_HUMAN (4-567): 0: 531: 35.39		WDR5_HUMAN (32-232): 5.32e-20: 94.4: 17.89
+	Sc
		1015332 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		UTP12_YEAST (33-155): 4.19e-12: 72.3: 6.30
+	Sc
		1015334 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		UTP12_YEAST (33-155): 4.19e-12: 72.3: 6.30
+	Hs
		903389 PRP31_HUMAN (160-581): 1.53e-125: 380: 19.91		WDR5_HUMAN (32-232): 5.32e-20: 94.4: 17.89