HitPredict

Interactor 1: NOP56 (O00567)
Nucleolar protein 56 (Nucleolar protein 5A)
Gene: NOP56

Interactor 2: BRX1 (Q8TDN6)
Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2)
Gene: BRIX1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 12777385
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0006364 - rRNA processing
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 594 Hs			1 353
+	Hs
		133613 NOP56_HUMAN (1-594): 0: 661: 100.00		IMP4_HUMAN (2-272): 6.92e-91: 275: 17.56
+	Hs
		108789 NOP56_HUMAN (1-594): 0: 661: 100.00		H0Y714_HUMAN (16-272): 3.9e-90: 273: 16.60
+	Sc
		866639 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		IMP4_YEAST (4-278): 4.96e-80: 248: 18.51
+	Hs
		133689 NOP56_HUMAN (1-594): 0: 661: 100.00		SSF1_HUMAN (54-228): 2.87e-21: 96.4: 15.22
+	Sc
		994475 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		BRX1_YEAST (40-305): 1.92e-92: 279: 45.32
+	Sc
		866641 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		IMP4_YEAST (4-278): 4.96e-80: 248: 18.51
+	Sc
		755354 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		RPF1_YEAST (4-269): 5.6e-62: 201: 15.33
+	Sc
		733987 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		RPF2_YEAST (71-267): 1.62e-13: 72.5: 19.56
+	Sc
		754941 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		SSF1_YEAST (39-230): 7.36e-18: 86.4: 14.88
+	Sc
		733990 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		RPF2_YEAST (71-267): 1.62e-13: 72.5: 19.56
+	Pf
		82933 C0H4A0_PLAF7 (165-576): 4e-93: 297: 21.31		Q8IB23_PLAF7 (3-264): 1.25e-58: 195: 13.57