HitPredict

Interactor 1: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Interactor 2: IF2B2 (Q9Y6M1)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)
Gene: IGF2BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	36950384
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2581 Hs			1 599
+	Hs
		128310 CHD8_HUMAN (1-2581): 0: 2318: 100.00		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		1336297 CHD8_HUMAN (1-2581): 0: 2318: 100.00		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		904149 CHD8_HUMAN (1-2581): 0: 2318: 100.00		HNRPK_HUMAN (386-596): 5.84e-18: 88.9: 17.09
+	Hs
		1018777 CHD3_HUMAN (385-2065): 0: 1037: 23.37		IF2B2_HUMAN (1-599): 1.06e-146: 438: 100.00
+	Hs
		128156 CHD3_HUMAN (385-2065): 0: 1037: 23.37		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		1018725 CHD3_HUMAN (385-2065): 0: 1037: 23.37		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		1059908 CHD4_HUMAN (500-2065): 0: 981: 23.88		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Dm
		332909 CHDM_DROME (439-2066): 0: 997: 22.94		Q9VZ69_DROME (169-595): 1.5e-79: 263: 40.78
+	Hs
		1018495 CHD3_HUMAN (385-2065): 0: 1037: 23.37		PCBP2_HUMAN (422-597): 7.25e-36: 140: 26.92
+	Hs
		903908 CHD3_HUMAN (385-2065): 0: 1037: 23.37		HNRPK_HUMAN (386-596): 5.84e-18: 88.9: 17.09
+	Hs
		1059629 CHD4_HUMAN (500-2065): 0: 981: 23.88		PCBP2_HUMAN (422-597): 7.25e-36: 140: 26.92
+	Hs
		959380 CHD3_HUMAN (385-2065): 0: 1037: 23.37		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01
+	Hs
		1018494 CHD3_HUMAN (385-2065): 0: 1037: 23.37		PCBP1_HUMAN (422-530): 8.21e-11: 65.8: 25.69
+	Hs
		903938 CHD4_HUMAN (500-2065): 0: 981: 23.88		HNRPK_HUMAN (386-596): 5.84e-18: 88.9: 17.09
+	Hs
		959423 CHD4_HUMAN (500-2065): 0: 981: 23.88		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01
+	Hs
		229365 SMCA5_HUMAN (687-1722): 0: 886: 26.82		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01
+	Hs
		846926 SMCA4_HUMAN (69-1478): 0: 806: 23.14		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01
+	Hs
		151488 CHD2_HUMAN (373-1741): 0: 803: 25.76		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01
+	Hs
		959734 CHD7_HUMAN (7-828): 2.19e-22: 108: 8.97		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01