HitPredict

Interactor 1: TRI39 (Q9HCM9)
E3 ubiquitin-protein ligase TRIM39 (EC 2.3.2.27) (RING finger protein 23) (RING-type E3 ubiquitin transferase TRIM39) (Testis-abundant finger protein) (Tripartite motif-containing protein 39)
Gene: TRIM39

Interactor 2: UB2D4 (Q9Y2X8)
Ubiquitin-conjugating enzyme E2 D4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D4) (HBUCE1) (Ubiquitin carrier protein D4) (Ubiquitin-protein ligase D4)
Gene: UBE2D4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.726

Property	Details
Experiments	25416956, 16189514, 32296183, 19549727, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 518 Hs			1 147
+	Hs
		849453 TRI39_HUMAN (1-518): 1.69e-173: 501: 100.00		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		919870 TRI39_HUMAN (1-518): 1.69e-173: 501: 100.00		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	Hs
		895921 TRI39_HUMAN (1-518): 1.69e-173: 501: 100.00		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84
+	Hs
		1297370 TRI39_HUMAN (1-518): 1.69e-173: 501: 100.00		UB2E2_HUMAN (4-146): 3.5e-75: 224: 64.34
+	Hs
		1282350 TRI39_HUMAN (1-518): 1.69e-173: 501: 100.00		UB2E3_HUMAN (4-146): 1.24e-74: 223: 64.34
+	Hs
		851889 TRI39_HUMAN (1-518): 1.69e-173: 501: 100.00		UB2E1_HUMAN (4-146): 4.67e-73: 218: 64.34
+	Hs
		896547 TRI39_HUMAN (1-518): 1.69e-173: 501: 100.00		UBE2N_HUMAN (4-147): 1.52e-69: 208: 46.53
+	Hs
		584907 RO52_HUMAN (15-513): 3.5e-141: 417: 38.92		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		584923 RO52_HUMAN (15-513): 3.5e-141: 417: 38.92		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	Hs
		584916 RO52_HUMAN (15-513): 3.5e-141: 417: 38.92		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84
+	Hs
		536760 TRI27_HUMAN (15-518): 7.9e-137: 407: 37.28		UB2D1_HUMAN (1-147): 4.61e-83: 241: 91.84
+	Hs
		536779 TRI27_HUMAN (15-518): 7.9e-137: 407: 37.28		UB2D2_HUMAN (1-147): 1.54e-82: 240: 93.20
+	Hs
		536772 TRI27_HUMAN (15-518): 7.9e-137: 407: 37.28		UB2D3_HUMAN (1-147): 1.56e-81: 238: 91.84
+	Hs
		584910 RO52_HUMAN (15-513): 3.5e-141: 417: 38.92		UB2E1_HUMAN (4-146): 4.67e-73: 218: 64.34
+	Hs
		536996 TRI27_HUMAN (15-518): 7.9e-137: 407: 37.28		UB2E2_HUMAN (4-146): 3.5e-75: 224: 64.34
+	Hs
		536965 TRI27_HUMAN (15-518): 7.9e-137: 407: 37.28		UB2E3_HUMAN (4-146): 1.24e-74: 223: 64.34
+	Hs
		536763 TRI27_HUMAN (15-518): 7.9e-137: 407: 37.28		UB2E1_HUMAN (4-146): 4.67e-73: 218: 64.34
+	Hs
		584918 RO52_HUMAN (15-513): 3.5e-141: 417: 38.92		UBE2N_HUMAN (4-147): 1.52e-69: 208: 46.53
+	Hs
		536757 TRI27_HUMAN (15-518): 7.9e-137: 407: 37.28		UBE2A_HUMAN (2-144): 4.45e-71: 211: 41.26
+	Hs
		536774 TRI27_HUMAN (15-518): 7.9e-137: 407: 37.28		UBE2N_HUMAN (4-147): 1.52e-69: 208: 46.53