HitPredict

Interactor 1: PNMA1 (Q8ND90)
Paraneoplastic antigen Ma1 (37 kDa neuronal protein) (Neuron- and testis-specific protein 1)
Gene: PNMA1

Interactor 2: PNMA2 (Q9UL42)
Paraneoplastic antigen Ma2 (40 kDa neuronal protein) (Onconeuronal antigen Ma2) (Paraneoplastic neuronal antigen MM2)
Gene: PNMA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

Property	Details
Experiments	33961781, 14676191, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PNMA~PNMA
Common GO terms	GO:0005730 - nucleolus GO:0043065 - positive regulation of apoptotic process
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 353 Hs			1 364
+	Hs
		1336450 PNMA1_HUMAN (1-353): 8.01e-177: 496: 100.00		PNMA5_HUMAN (1-357): 8.16e-168: 477: 45.81
+	Hs
		1336414 PNMA1_HUMAN (1-353): 8.01e-177: 496: 100.00		PNMA1_HUMAN (1-332): 1.46e-163: 462: 47.75
+	Hs
		1461424 PNMA3_HUMAN (1-337): 5.96e-162: 462: 49.41		PNMA3_HUMAN (1-350): 1e-170: 485: 49.58
+	Hs
		1336428 PNMA1_HUMAN (1-353): 8.01e-177: 496: 100.00		MOAP1_HUMAN (1-333): 3.85e-156: 444: 46.25
+	Hs
		1400215 PNMA5_HUMAN (1-338): 1.51e-161: 461: 46.90		PNMA5_HUMAN (1-357): 8.16e-168: 477: 45.81
+	Hs
		1385135 PNMA5_HUMAN (1-338): 1.51e-161: 461: 46.90		MOAP1_HUMAN (1-333): 3.85e-156: 444: 46.25
+	Hs
		1385149 MOAP1_HUMAN (1-353): 2.29e-149: 426: 55.87		PNMA2_HUMAN (1-364): 2.26e-169: 478: 100.00
+	Hs
		511039 PNMA1_HUMAN (1-353): 8.01e-177: 496: 100.00		PNM6A_HUMAN (1-351): 4.56e-136: 395: 41.13
+	Hs
		1385130 MOAP1_HUMAN (1-353): 2.29e-149: 426: 55.87		MOAP1_HUMAN (1-333): 3.85e-156: 444: 46.25
+	Hs
		511042 MOAP1_HUMAN (1-353): 2.29e-149: 426: 55.87		PNM6A_HUMAN (1-351): 4.56e-136: 395: 41.13
+	Hs
		511049 PNMA2_HUMAN (1-329): 4.44e-144: 413: 48.50		PNM6A_HUMAN (1-351): 4.56e-136: 395: 41.13
+	Hs
		1244020 PNMA1_HUMAN (1-353): 8.01e-177: 496: 100.00		ZCH12_HUMAN (120-351): 1.45e-91: 281: 35.29
+	Hs
		1290009 PNMA1_HUMAN (1-353): 8.01e-177: 496: 100.00		PNM8A_HUMAN (1-160): 8.12e-66: 216: 45.00
+	Hs
		1244032 PNMA2_HUMAN (1-329): 4.44e-144: 413: 48.50		ZCH12_HUMAN (120-351): 1.45e-91: 281: 35.29
+	Hs
		1290017 MOAP1_HUMAN (1-353): 2.29e-149: 426: 55.87		PNM8A_HUMAN (1-160): 8.12e-66: 216: 45.00
+	Hs
		1290056 PNMA2_HUMAN (1-329): 4.44e-144: 413: 48.50		PNM8A_HUMAN (1-160): 8.12e-66: 216: 45.00