Interactor 1: LY96 (Q9JHF9)
Lymphocyte antigen 96 (Ly-96) (ESOP-1) (Protein MD-2)
Gene: LY96

Interactor 2: TLR4 (Q9QUK6)
Toll-like receptor 4 (CD antigen CD284)
Gene: TLR4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.726

The method score is based on:

Property Details
Experiments 21857663, 22532668, 15908446, 12496426, 17803912
Identification Methods molecular sieving, x-ray crystallography, comigration in non denaturing gel electrophoresis, x ray scattering, anti tag coimmunoprecipitation, fluorescence-activated cell sorting
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001530 - lipopolysaccharide binding
GO:0001875 - lipopolysaccharide immune receptor activity
GO:0002224 - toll-like receptor signaling pathway
GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
and 8 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 160
Mm

1 835
+ Hs
+ Hs

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Last updated: 15 Jul 2024