HitPredict

Interactor 1: LRP1B (Q9JI18)
Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)
Gene: LRP1B

Interactor 2: JIP1 (Q9WVI9)
C-Jun-amino-terminal kinase-interacting protein 1 (JIP-1) (JNK-interacting protein 1) (Islet-brain-1) (IB-1) (JNK MAP kinase scaffold protein 1) (Mitogen-activated protein kinase 8-interacting protein 1)
Gene: Mapk8ip1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	19071120
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4599 Mm			1 707
+	Mm
		1322325 LRP1B_MOUSE (1-4599): 0: 3310: 100.00		JIP2_MOUSE (21-256): 1e-44: 174: 29.46
+	Mm
		1257662 LRP4_MOUSE (2814-3109): 2.43e-13: 79.5: 16.41		JIP1_MOUSE (1-707): 0: 783: 100.00
+	Mm
		69888 B1AXJ3_MOUSE (3229-3433): 4.69e-12: 74.9: 16.00		JIP1_MOUSE (1-707): 0: 783: 100.00
+	Mm
		1266182 LRP8_MOUSE (2467-2659): 1.42e-11: 73.4: 21.89		JIP1_MOUSE (1-707): 0: 783: 100.00
+	Mm
		57563 LRP2_MOUSE (4024-4363): 2.63e-11: 73: 11.75		JIP1_MOUSE (1-707): 0: 783: 100.00
+	Hs
		957662 LRP2_HUMAN (4065-4360): 3.92e-10: 69.1: 12.42		JIP1_HUMAN (1-707): 0: 730: 92.42
+	Hs
		957621 LRP2_HUMAN (4065-4360): 3.92e-10: 69.1: 12.42		ANS1B_HUMAN (419-696): 2.27e-61: 225: 18.51
+	Mm
		69886 B1AXJ3_MOUSE (3229-3433): 4.69e-12: 74.9: 16.00		JIP2_MOUSE (21-256): 1e-44: 174: 29.46
+	Mm
		1266181 LRP8_MOUSE (2467-2659): 1.42e-11: 73.4: 21.89		JIP2_MOUSE (21-256): 1e-44: 174: 29.46
+	Mm
		57562 LRP2_MOUSE (4024-4363): 2.63e-11: 73: 11.75		JIP2_MOUSE (21-256): 1e-44: 174: 29.46
+	Hs
		957599 LRP2_HUMAN (4065-4360): 3.92e-10: 69.1: 12.42		JIP2_HUMAN (21-266): 8.52e-45: 174: 32.30
+	Mm
		966336 NOTC1_MOUSE (16-285): 5.08e-14: 81.8: 11.91		NUMB_MOUSE (524-700): 1.37e-40: 160: 18.38
+	Mm
		1265299 LRP1_MOUSE (25-276): 2.14e-09: 66.8: 14.73		JIP2_MOUSE (21-256): 1e-44: 174: 29.46
+	Dm
		422847 NOTCH_DROME (766-1147): 1.33e-12: 77.2: 12.42		Q9VCM6_DROME (523-695): 1.12e-37: 153: 21.14
+	Dm
		422717 NOTCH_DROME (766-1147): 1.33e-12: 77.2: 12.42		NUMB_DROME (537-700): 1.21e-36: 147: 20.00
+	Hs
		253552 LRP2_HUMAN (4065-4360): 3.92e-10: 69.1: 12.42		CAPON_HUMAN (541-703): 1.09e-36: 146: 20.69
+	Mm
		57558 LRP2_MOUSE (4024-4363): 2.63e-11: 73: 11.75		ARH_MOUSE (527-692): 5.9e-37: 142: 17.54
+	Hs
		957612 LRP2_HUMAN (4065-4360): 3.92e-10: 69.1: 12.42		ARH_HUMAN (543-702): 9.88e-38: 144: 19.14
+	Hs
		351073 LDLR_HUMAN (4245-4561): 3.74e-10: 68.7: 13.40		ARH_HUMAN (543-702): 9.88e-38: 144: 19.14
+	Rn
		88518 LRP2_RAT (4023-4360): 9.07e-11: 71: 11.26		ARH_RAT (527-692): 2.01e-34: 135: 17.54