Interactor 1: PRKN (Q9JK66)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)
Gene: PRKN

Interactor 2: PRKN (Q9JK66)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)
Gene: PRKN

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.888

The method score is based on:

Property Details
Experiments 24337465, 35042405, 23258539, 23661642
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ubiquitin~ubiquitin, ubiquitin~zf-RING_12, ubiquitin~zf-RING_14, zf-RING_12~zf-RING_12, zf-RING_12~zf-RING_14
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000139 - Golgi membrane
GO:0000151 - ubiquitin ligase complex
GO:0000209 - protein polyubiquitination
GO:0000266 - mitochondrial fission
and 152 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 465
Rn

1 465
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+ Mm
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Last updated: 15 Jul 2024