HitPredict - High confidence protein-protein interactions

Interactor 1: NCOA6 (Q9JLI4)
Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)
Gene: NCOA6

Interactor 2: NCOA6 (Q9JLI4)
Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)
Gene: NCOA6

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	10866662
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001541 - ovarian follicle development GO:0002793 - positive regulation of peptide secretion GO:0003682 - chromatin binding GO:0003713 - transcription coactivator activity GO:0005634 - nucleus and 26 others more... GO:0005667 - transcription regulator complex GO:0006352 - DNA-templated transcription initiation GO:0006974 - DNA damage response GO:0007420 - brain development GO:0007507 - heart development GO:0010468 - regulation of gene expression GO:0019899 - enzyme binding GO:0019904 - protein domain specific binding GO:0030099 - myeloid cell differentiation GO:0030331 - nuclear estrogen receptor binding GO:0030374 - nuclear receptor coactivator activity GO:0032991 - protein-containing complex GO:0035097 - histone methyltransferase complex GO:0035259 - nuclear glucocorticoid receptor binding GO:0035774 - positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0042809 - nuclear vitamin D receptor binding GO:0042974 - nuclear retinoic acid receptor binding GO:0042975 - peroxisome proliferator activated receptor binding GO:0044666 - MLL3/4 complex GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046965 - nuclear retinoid X receptor binding GO:0046966 - nuclear thyroid hormone receptor binding GO:0060716 - labyrinthine layer blood vessel development GO:0140463 - chromatin-protein adaptor activity GO:1990226 - histone methyltransferase binding
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	418
Rn

1	418

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024