HitPredict

Interactor 1: CUL3 (Q9JLV5)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: KEAP1 (Q9Z2X8)
Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2)
Gene: KEAP1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 28887507, 30261176
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BACK~Cullin, BTB~Cullin
Common GO terms GO:0001701 - in utero embryonic development
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination
GO:0031463 - Cul3-RING ubiquitin ligase complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 768
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1 624
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024