Interactor 1: DDX3X (O00571)
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
Gene: DDX3X

Interactor 2: RIGI (O95786)
Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
Gene: RIGI

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 20127681
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, DEAD~RIG-I_C, DEAD~RIG-I_C-RD, Helicase_C~Helicase_C, Helicase_C~RIG-I_C, Helicase_C~RIG-I_C-RD
Common GO terms GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009615 - response to virus
and 6 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 662
Hs

1 925
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Last updated: 15 Jul 2024