HitPredict

Interactor 1: DDX3X (O00571)
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
Gene: DDX3X

Interactor 2: HSF1 (Q00613)
Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1)
Gene: HSF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

The method score is based on:

Property	Details
Experiments	36339263, 35906200
Identification Methods	affinity chromatography technology
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005813 - centrosome and 5 others more... GO:0005829 - cytosol GO:0010628 - positive regulation of gene expression GO:0010629 - negative regulation of gene expression GO:0031333 - negative regulation of protein-containing complex assembly GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	662
Hs

1	529

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024