HitPredict

Interactor 1: DDB1A (Q9M0V3)
DNA damage-binding protein 1a (UV-damaged DNA-binding protein 1a) (DDB1a)
Gene: DDB1A

Interactor 2: HTD1 (Q9ZUN8)
Protein HEAT STRESS TOLERANT DWD 1
Gene: HTD1

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	25358503
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	GO:0016567 - protein ubiquitination GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1088 At			1 469
+	At
		186944 DDB1A_ARATH (1-1088): 0: 1321: 100.00		MSI1_ARATH (23-469): 1.08e-81: 260: 22.61
+	At
		1154740 DDB1A_ARATH (1-1088): 0: 1321: 100.00		FY_ARATH (4-341): 2.73e-43: 163: 18.87
+	Hs
		997738 DDB1_HUMAN (3-1088): 0: 1206: 52.44		RBBP4_HUMAN (10-462): 2.5e-87: 275: 25.00
+	Hs
		1082202 DDB1_HUMAN (3-1088): 0: 1206: 52.44		RBBP7_HUMAN (13-469): 2.41e-85: 270: 23.93
+	At
		221826 DDB1B_ARATH (1-1088): 0: 1308: 91.27		FY_ARATH (4-341): 2.73e-43: 163: 18.87
+	At
		187019 DDB1A_ARATH (1-1088): 0: 1321: 100.00		MSI4_ARATH (25-320): 1.59e-25: 111: 12.58
+	At
		186951 DDB1A_ARATH (1-1088): 0: 1321: 100.00		MSI3_ARATH (309-469): 2.65e-23: 103: 16.58
+	At
		187004 DDB1B_ARATH (1-1088): 0: 1308: 91.27		MSI4_ARATH (25-320): 1.59e-25: 111: 12.58
+	At
		186950 DDB1B_ARATH (1-1088): 0: 1308: 91.27		MSI3_ARATH (309-469): 2.65e-23: 103: 16.58
+	At
		824877 DDB1A_ARATH (1-1088): 0: 1321: 100.00		GBB_ARATH (199-392): 2.34e-11: 67: 28.06
+	Hs
		903254 DDB1_HUMAN (3-1088): 0: 1206: 52.44		WDR5_HUMAN (23-297): 1.77e-42: 155: 13.86
+	Hs
		1082374 DDB1_HUMAN (3-1088): 0: 1206: 52.44		TBL1R_HUMAN (2-255): 8.5e-24: 105: 9.06
+	Hs
		1082263 DDB1_HUMAN (3-1088): 0: 1206: 52.44		WDR5B_HUMAN (302-463): 3.59e-24: 104: 14.82
+	Hs
		1082355 DDB1_HUMAN (3-1088): 0: 1206: 52.44		GRWD1_HUMAN (298-466): 3.49e-23: 103: 15.98
+	Ce
		219829 O44985_CAEEL (3-1085): 0: 951: 20.11		LIN53_CAEEL (20-468): 3.68e-82: 261: 23.57
+	Hs
		1073127 SF3B3_HUMAN (3-1085): 0: 1018: 21.15		GRWD1_HUMAN (298-466): 3.49e-23: 103: 15.98
+	Ce
		954081 CPSF1_CAEEL (622-1087): 9.79e-101: 350: 18.80		LIN53_CAEEL (20-468): 3.68e-82: 261: 23.57
+	Hs
		1014128 CPSF1_HUMAN (632-1087): 1.83e-118: 400: 22.72		TAF5_HUMAN (119-342): 1.91e-47: 176: 20.41
+	At
		1154738 CPSF1_ARATH (31-519): 4.99e-100: 347: 17.25		FY_ARATH (4-341): 2.73e-43: 163: 18.87