HitPredict

Interactor 1: DDX3X (O00571)
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
Gene: DDX3X

Interactor 2: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29395067, 30209976, 23663784
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0010494 - cytoplasmic stress granule GO:0035613 - RNA stem-loop binding GO:1901224 - positive regulation of non-canonical NF-kappaB signal transduction
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 662 Hs			1 1133
+	Hs
		1136209 DDX17_HUMAN (122-661): 2.1e-152: 459: 36.38		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		134212 DDX3X_HUMAN (1-662): 0: 614: 100.00		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1271665 DDX17_HUMAN (122-661): 2.1e-152: 459: 36.38		RC3H2_HUMAN (1-1107): 0: 1494: 51.72