HitPredict

Interactor 1: DDX3X (O00571)
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
Gene: DDX3X

Interactor 2: LARP4 (Q71RC2)
La-related protein 4 (La ribonucleoprotein domain family member 4)
Gene: LARP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0008143 - poly(A) binding GO:0010494 - cytoplasmic stress granule GO:0045727 - positive regulation of translation
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 662 Hs			1 724
+	Hs
		134141 DDX3X_HUMAN (1-662): 0: 614: 100.00		LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70
+	Hs
		134068 DDX3X_HUMAN (1-662): 0: 614: 100.00		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		134091 DDX3X_HUMAN (1-662): 0: 614: 100.00		LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72
+	Hs
		181706 DDX3Y_HUMAN (1-662): 0: 602: 91.84		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		571479 DDX5_HUMAN (90-658): 2.78e-160: 476: 35.70		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		1116430 DDX17_HUMAN (122-661): 2.1e-152: 459: 36.38		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Sc
		624057 DBP2_YEAST (72-578): 2.04e-147: 440: 37.31		LHP1_YEAST (92-299): 2.37e-39: 148: 16.60