HitPredict

Interactor 1: Q9NF31 (Q9NF31)
EG:BACN25G24.3 protein (Fbgn0004860;ph-d protein) (Polyhomeotic distal, isoform B)
Gene: ph-d

Interactor 2: RING1 (Q9VB08)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RING1) (Sex comb extra protein) (dRING protein) (dRING1)
Gene: Sce

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	18923078, 25415640, 22491092, 27151979, 25468754
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005730 - nucleolus GO:0008270 - zinc ion binding GO:0035102 - PRC1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1359 Dm			1 435
+	Dm
		764510 PHP_DROME (1-1354): 6.03e-88: 317: 78.73		RING1_DROME (1-435): 5e-109: 330: 100.00
+	Dm
		627168 Q9NF31_DROME (1-1359): 5.21e-99: 348: 100.00		SUZ2_DROME (25-351): 4.29e-50: 184: 13.02
+	Dm
		627164 PHP_DROME (1-1354): 6.03e-88: 317: 78.73		SUZ2_DROME (25-351): 4.29e-50: 184: 13.02
+	Hs
		987993 PHC3_HUMAN (325-1351): 2.12e-51: 199: 18.28		RING1_HUMAN (9-434): 1.73e-78: 250: 34.98
+	Dm
		1374688 Q9W523_DROME (1-1359): 1.38e-98: 349: 100.00		Q9VV77_DROME (31-141): 3.13e-23: 99: 24.56
+	Dm
		1341979 Q9NF31_DROME (1-1359): 5.21e-99: 348: 100.00		Q9VV77_DROME (31-141): 3.13e-23: 99: 24.56
+	Dm
		764516 PHP_DROME (1-1354): 6.03e-88: 317: 78.73		Q9VV77_DROME (31-141): 3.13e-23: 99: 24.56
+	Hs
		718412 PHC3_HUMAN (325-1351): 2.12e-51: 199: 18.28		PCGF2_HUMAN (29-363): 3.49e-50: 175: 12.57
+	Hs
		1242728 PHC3_HUMAN (325-1351): 2.12e-51: 199: 18.28		RING2_HUMAN (198-434): 9.74e-49: 171: 28.00
+	Hs
		718028 PHC3_HUMAN (325-1351): 2.12e-51: 199: 18.28		BMI1_HUMAN (29-324): 2e-47: 167: 12.73
+	Dr
		1193369 PHC2_DANRE (504-1351): 2.62e-50: 194: 19.04		RING2_DANRE (198-434): 3.22e-48: 169: 27.71
+	Hs
		554277 MUC1_HUMAN (21-997): 1.1e-48: 192: 9.40		BMI1_HUMAN (29-324): 2e-47: 167: 12.73
+	Mm
		620790 PHC3_MOUSE (326-1351): 1.43e-47: 187: 17.33		PCGF2_MOUSE (29-363): 8.35e-49: 171: 12.87
+	Mm
		639476 PHC3_MOUSE (326-1351): 1.43e-47: 187: 17.33		BMI1_MOUSE (29-326): 2.02e-47: 167: 13.03
+	Dr
		1225025 PHC2_DANRE (504-1351): 2.62e-50: 194: 19.04		BMI1A_DANRE (29-322): 4.98e-38: 142: 15.43
+	Hs
		1242734 PHC3_HUMAN (325-1351): 2.12e-51: 199: 18.28		PCGF6_HUMAN (21-160): 1.24e-34: 133: 22.38
+	Dr
		1186373 PHC2_DANRE (504-1351): 2.62e-50: 194: 19.04		BMI1B_DANRE (29-355): 3.33e-36: 137: 12.95
+	Hs
		1108519 PHC3_HUMAN (325-1351): 2.12e-51: 199: 18.28		PCGF3_HUMAN (34-211): 2.54e-32: 124: 18.68
+	Hs
		1242732 PHC3_HUMAN (325-1351): 2.12e-51: 199: 18.28		PCGF1_HUMAN (23-127): 1.04e-30: 120: 24.07
+	Hs
		1197572 PHC3_HUMAN (325-1351): 2.12e-51: 199: 18.28		PCGF5_HUMAN (37-145): 6.14e-18: 85.1: 29.46