Interactor 1: FMR1 (Q9NFU0)
Fragile X messenger ribonucleoprotein 1 homolog (FMRP) (dFMR1)
Gene: FMR1

Interactor 2: FMR1 (Q9NFU0)
Fragile X messenger ribonucleoprotein 1 homolog (FMRP) (dFMR1)
Gene: FMR1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 12460546, 12368261
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains KH_1~KH_1, KH_9~Tudor_FRX1
Common GO terms GO:0000139 - Golgi membrane
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000900 - mRNA regulatory element binding translation repressor activity
GO:0001934 - positive regulation of protein phosphorylation
GO:0002052 - positive regulation of neuroblast proliferation
and 97 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 684
Dm

1 684
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024