HitPredict

Interactor 1: FMR1 (Q9NFU0)
Fragile X messenger ribonucleoprotein 1 homolog (FMRP) (dFMR1)
Gene: FMR1

Interactor 2: CYFIP (Q9VF87)
Cytoplasmic FMR1-interacting protein (Specifically Rac1-associated protein 1)
Gene: CYFIP

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	12818175, 25908854
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0006417 - regulation of translation GO:0007411 - axon guidance GO:0043005 - neuron projection GO:0050807 - regulation of synapse organization
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 684 Dm			1 1291
+	Hs
		989051 FMR1_HUMAN (1-456): 0: 709: 40.27		CYFP2_HUMAN (1-1275): 0: 2003: 64.67
+	Hs
		843841 FXR1_HUMAN (1-412): 0: 691: 46.01		CYFP2_HUMAN (1-1275): 0: 2003: 64.67
+	Mm
		729478 FMR1_MOUSE (1-456): 0: 672: 38.22		CYFP2_MOUSE (1-1275): 0: 2011: 65.94
+	Hs
		988969 FMR1_HUMAN (1-456): 0: 709: 40.27		CYFP1_HUMAN (1-1275): 0: 1973: 65.57
+	Hs
		844189 FXR2_HUMAN (4-484): 0: 664: 43.92		CYFP2_HUMAN (1-1275): 0: 2003: 64.67
+	Hs
		843759 FXR1_HUMAN (1-412): 0: 691: 46.01		CYFP1_HUMAN (1-1275): 0: 1973: 65.57
+	Mm
		729528 FMR1_MOUSE (1-456): 0: 672: 38.22		CYFP1_MOUSE (1-1275): 0: 1966: 65.18
+	Hs
		844119 FXR2_HUMAN (4-484): 0: 664: 43.92		CYFP1_HUMAN (1-1275): 0: 1973: 65.57
+	Mm
		1131102 Q8BPK8_MOUSE (1-342): 0: 614: 45.48		CYFP2_MOUSE (1-1275): 0: 2011: 65.94