HitPredict

Interactor 1: Q9NHP2 (Q9NHP2)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: POSH

Interactor 2: Q9VB05 (Q9VB05)
ALG-2 interacting protein X (LD25543p)
Gene: ALiX

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	16698022
Identification Methods	pull down, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046330 - positive regulation of JNK cascade
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 838 Dm			1 836
+	Dm
		1180080 Q7K4D1_DROME (1-838): 3.25e-133: 419: 99.76		Q9VB05_DROME (1-836): 0: 576: 100.00
+	Hs
		1260385 SH3G1_HUMAN (70-197): 1.68e-36: 143: 29.86		PDC6I_HUMAN (1-831): 1.81e-177: 535: 40.28
+	Mm
		1143918 SH3G1_MOUSE (82-197): 6.23e-38: 147: 31.06		PDC6I_MOUSE (1-831): 7.33e-168: 510: 39.89
+	Hs
		1191850 SH3R1_HUMAN (365-836): 2.59e-21: 101: 14.20		PDC6I_HUMAN (1-831): 1.81e-177: 535: 40.28
+	Hs
		1078881 ITSN1_HUMAN (48-202): 7.34e-17: 88: 18.07		PDC6I_HUMAN (1-831): 1.81e-177: 535: 40.28
+	Hs
		1260386 SH3G2_HUMAN (193-254): 7.93e-16: 81.9: 38.71		PDC6I_HUMAN (1-831): 1.81e-177: 535: 40.28
+	Hs
		924726 GRB2_HUMAN (419-481): 2.7e-16: 80.7: 33.33		PDC6I_HUMAN (1-831): 1.81e-177: 535: 40.28
+	Mm
		1143926 SH3G2_MOUSE (193-254): 5.31e-16: 82.3: 38.71		PDC6I_MOUSE (1-831): 7.33e-168: 510: 39.89
+	Mm
		1141174 GRB2_MOUSE (416-481): 2.55e-16: 80.7: 31.82		PDC6I_MOUSE (1-831): 7.33e-168: 510: 39.89
+	Ce
		104698 SRBS1_CAEEL (613-835): 8.31e-22: 103: 17.49		ALXA_CAEEL (4-831): 6.57e-152: 469: 37.01
+	Hs
		1078907 ITSN1_HUMAN (48-202): 7.34e-17: 88: 18.07		PTN23_HUMAN (3-833): 8.29e-127: 418: 22.46
+	Hs
		1307434 SH3G2_HUMAN (193-254): 7.93e-16: 81.9: 38.71		PTN23_HUMAN (3-833): 8.29e-127: 418: 22.46
+	Hs
		275227 GRAP2_HUMAN (765-836): 7.7e-16: 81.5: 25.00		PTN23_HUMAN (3-833): 8.29e-127: 418: 22.46
+	Hs
		924858 GRB2_HUMAN (419-481): 2.7e-16: 80.7: 33.33		PTN23_HUMAN (3-833): 8.29e-127: 418: 22.46
+	Mm
		292687 GRAP2_MOUSE (50-194): 2.58e-16: 83: 17.24		PTN23_MOUSE (3-829): 1.28e-121: 404: 21.38
+	Hs
		978569 SH3G1_HUMAN (70-197): 1.68e-36: 143: 29.86		PRB3_HUMAN (699-834): 2.22e-13: 74.5: 16.67
+	Hs
		235528 VINEX_HUMAN (273-836): 2.28e-17: 89: 11.86		PKHA7_HUMAN (576-832): 2.31e-29: 128: 16.54
+	Hs
		924640 GRB2_HUMAN (419-481): 2.7e-16: 80.7: 33.33		PKHA7_HUMAN (576-832): 2.31e-29: 128: 16.54
+	Hs
		1073686 SH3R1_HUMAN (365-836): 2.59e-21: 101: 14.20		SF3A2_HUMAN (710-832): 1.44e-13: 76.1: 13.71
+	Hs
		924592 GRB2_HUMAN (419-481): 2.7e-16: 80.7: 33.33		SF3A2_HUMAN (710-832): 1.44e-13: 76.1: 13.71