HitPredict

Interactor 1: ARFG3 (Q9NP61)
ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3)
Gene: ARFGAP3

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 516 Hs			1 1620
+	Hs
		434292 ARFG3_HUMAN (1-516): 1.38e-169: 491: 100.00		RET_HUMAN (842-1477): 4.8e-137: 455: 23.56
+	Hs
		169208 ARFG3_HUMAN (1-516): 1.38e-169: 491: 100.00		MUSK_HUMAN (983-1391): 2.02e-118: 396: 29.98
+	Hs
		508212 ARFG3_HUMAN (1-516): 1.38e-169: 491: 100.00		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		435771 ARFG3_HUMAN (1-516): 1.38e-169: 491: 100.00		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		434240 ARFG2_HUMAN (2-516): 4.95e-137: 407: 53.61		RET_HUMAN (842-1477): 4.8e-137: 455: 23.56
+	Hs
		169187 ARFG2_HUMAN (2-516): 4.95e-137: 407: 53.61		MUSK_HUMAN (983-1391): 2.02e-118: 396: 29.98
+	Hs
		508103 ARFG2_HUMAN (2-516): 4.95e-137: 407: 53.61		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		385560 ARFG3_HUMAN (1-516): 1.38e-169: 491: 100.00		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		1081615 ARFG3_HUMAN (1-516): 1.38e-169: 491: 100.00		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03
+	Hs
		665688 GIT1_HUMAN (17-431): 6.08e-73: 247: 16.15		EPHB2_HUMAN (938-1436): 2.19e-123: 416: 23.26
+	Mm
		1142639 ASAP2_MOUSE (6-410): 6.66e-66: 231: 14.25		ERBB4_MOUSE (882-1541): 1.06e-121: 416: 21.23
+	Hs
		1081534 ARFG2_HUMAN (2-516): 4.95e-137: 407: 53.61		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03
+	Hs
		508262 ASAP1_HUMAN (2-459): 1.98e-65: 231: 15.53		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		195794 ASAP2_HUMAN (6-409): 1.78e-72: 250: 15.66		FAK2_HUMAN (1054-1518): 4.66e-109: 374: 27.45
+	Hs
		1052847 GIT1_HUMAN (17-431): 6.08e-73: 247: 16.15		FAK2_HUMAN (1054-1518): 4.66e-109: 374: 27.45
+	Rn
		936857 ARFG1_RAT (1-416): 1.65e-70: 232: 24.48		FAK2_RAT (1054-1496): 1.93e-111: 380: 29.24
+	Mm
		1351539 ASAP1_MOUSE (2-459): 1.64e-65: 231: 16.21		FAK2_MOUSE (1061-1496): 2.01e-110: 378: 28.31
+	Hs
		195775 ASAP2_HUMAN (6-409): 1.78e-72: 250: 15.66		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		385765 GIT1_HUMAN (17-431): 6.08e-73: 247: 16.15		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		385705 ASAP1_HUMAN (2-459): 1.98e-65: 231: 15.53		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07