HitPredict

Interactor 1: HM20A (Q9NP66)
High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein 1) (HMG domain-containing protein HMGX1)
Gene: HMG20A

Interactor 2: TCF20 (Q9UGU0)
Transcription factor 20 (TCF-20) (Nuclear factor SPBP) (Protein AR1) (Stromelysin-1 PDGF-responsive element-binding protein) (SPRE-binding protein)
Gene: TCF20

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 347 Hs			1 1960
+	Mm
		1322170 HM20A_MOUSE (1-347): 4.1e-77: 242: 95.97		TCF20_MOUSE (1-1960): 0: 860: 89.91
+	Hs
		818564 SOX2_HUMAN (68-269): 3.13e-31: 121: 15.42		TCF20_HUMAN (1-1960): 0: 925: 100.00
+	Hs
		1332328 SOX17_HUMAN (14-208): 2.05e-29: 118: 15.90		TCF20_HUMAN (1-1960): 0: 925: 100.00
+	Hs
		1191026 HM20A_HUMAN (1-347): 9.42e-80: 249: 100.00		RAI1_HUMAN (1-1933): 2.26e-103: 371: 20.28
+	Mm
		1143137 HM20A_MOUSE (1-347): 4.1e-77: 242: 95.97		RAI1_MOUSE (1-1933): 5.16e-102: 367: 19.85
+	Hs
		996738 SSRP1_HUMAN (1-266): 7.41e-32: 128: 16.30		RAI1_HUMAN (1-1933): 2.26e-103: 371: 20.28
+	Hs
		975232 SSRP1_HUMAN (1-266): 7.41e-32: 128: 16.30		KMT2A_HUMAN (1765-1933): 1.16e-32: 142: 20.00
+	Hs
		817951 SOX2_HUMAN (68-269): 3.13e-31: 121: 15.42		KMT2A_HUMAN (1765-1933): 1.16e-32: 142: 20.00
+	Hs
		867119 CIC_HUMAN (27-227): 1.8e-32: 130: 17.24		SC24C_HUMAN (143-516): 5.55e-10: 66.9: 16.14
+	Hs
		257583 SOX2_HUMAN (68-269): 3.13e-31: 121: 15.42		ANR17_HUMAN (6-473): 7.33e-11: 70.2: 10.33
+	Hs
		152610 SOX2_HUMAN (68-269): 3.13e-31: 121: 15.42		KMT2D_HUMAN (207-917): 2.24e-09: 65.3: 9.99
+	Hs
		152611 SOX9_HUMAN (10-266): 5.98e-30: 121: 13.21		KMT2D_HUMAN (207-917): 2.24e-09: 65.3: 9.99
+	Hs
		818266 SOX2_HUMAN (68-269): 3.13e-31: 121: 15.42		KMT2C_HUMAN (307-902): 2.88e-09: 64.9: 11.15
+	Hs
		818819 SOX9_HUMAN (10-266): 5.98e-30: 121: 13.21		KMT2C_HUMAN (307-902): 2.88e-09: 64.9: 11.15
+	Hs
		152690 SOX17_HUMAN (14-208): 2.05e-29: 118: 15.90		KMT2D_HUMAN (207-917): 2.24e-09: 65.3: 9.99
+	Hs
		1243843 SOX17_HUMAN (14-208): 2.05e-29: 118: 15.90		KMT2C_HUMAN (307-902): 2.88e-09: 64.9: 11.15
+	Hs
		449779 HMGB1_HUMAN (97-265): 2.13e-15: 76.2: 19.65		TITIN_HUMAN (744-1529): 2.73e-10: 68.4: 11.54